Dr. William DeBello

picture of william

Position Title
Associate Professor

NPB, Center for Neuroscience

Center for Neuroscience


1996    PhD    (Neurobiology)    Duke University
1990    BS    (Biology)    Stanford University

Research Interests

The Barn Owl Connectome Project

Our current goal is to reconstruct the complete wiring diagram of local circuits in the barn owl auditory localization pathway. This is a classic model system for studying the neural bases of information processing, plasticity and learning. Our integrative approach combines in vivo electrophysiology, auditory and visual receptive field mapping, tracer injection, immmunohistochemistry, confocal microscopy, automated transmission electron microscopy, 3D visualization, computer simulation and bootstrap analysis. We hope to better understand how individual life experience is encoded by changes in wiring patterns, and by extension, to shed light on principles of neural processing that are employed across brain regions and across species.


Presidential Early Career Award for Scientists and Engineers

Frontiers of Science Symposium, National Academies

Department and Center Affiliations

Center for Neuroscience

Department of Neurobiology, Phsyiology, and Behavior

CBS Grad Group Affiliations


Specialties / Focus


  • Cellular and Molecular Neurobiology
  • Development and Plasticity
  • Systems Neuroscience


SOM rm 106/317

  • DeBello Lab: Will DeBello, Tom McBride

Teaching Interests

Plasticity and learning, auditory system, human physiology, seminar speaking.